Selected Publications:
Genetics of Breast Cancer in Latinas:
Weitzel JN, Neuhausen SL, Adamson A, Tao S, Ricker C, Maoz A, Rosenblatt M, Nehoray B, Sand S, Steele L, Unzeitig G, Feldman N, Blanco AM, Hu D, Huntsman S, Castillo D, Haiman C, Slavin T, Ziv E. Pathogenic and likely pathogenic variants in PALB2, CHEK2, and other known breast cancer susceptibility genes among 1054 BRCA-negative Hispanics with breast cancer. Cancer. 2019. Epub 2019/06/18. doi: 10.1002/cncr.32083. PubMed PMID: 31206626.
Hoffman J, Fejerman L, Hu D, Huntsman S, Li M, John EM, Torres-Mejia G, Kushi L, Ding YC, Weitzel J, Neuhausen SL, Lott P, Consortium C, Echeverry M, Carvajal-Carmona L, Burchard E, Eng C, Long J, Zheng W, Olopade O, Huo D, Haiman C, Ziv E. Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas. Breast Cancer Res. 2019;21(1):3. Epub 2019/01/16. doi: 10.1186/s13058-018-1085-9. PubMed PMID: 30642363; PMCID: PMC6332913.
Fejerman L, Ahmadiyeh N, Hu D, Huntsman S, Beckman KB, Caswell JL, Tsung K, John EM, Torres-Mejia G, Carvajal-Carmona L, Echeverry MM, Tuazon AM, Ramirez C, Consortium C, Gignoux CR, Eng C, Gonzalez-Burchard E, Henderson B, Le Marchand L, Kooperberg C, Hou L, Agalliu I, Kraft P, Lindstrom S, Perez-Stable EJ, Haiman CA, Ziv E. Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25. Nat Commun. 2014;5:5260. Epub 2014/10/21. doi: 10.1038/ncomms6260. PubMed PMID: 25327703; PMCID: PMC4204111.
Fejerman L, Hu D, Huntsman S, John EM, Stern MC, Haiman CA, Perez-Stable EJ, Ziv E. Genetic ancestry and risk of mortality among U.S. Latinas with breast cancer. Cancer research. 2013;73(24):7243-53. doi: 10.1158/0008-5472.CAN-13-2014. PubMed PMID: 24177181; PMCID: 3881587.
Fejerman L, Chen GK, Eng C, Huntsman S, Hu D, Williams A, Pasaniuc B, John EM, Via M, Gignoux C, Ingles S, Monroe KR, Kolonel LN, Torres-Mejia G, Perez-Stable EJ, Burchard EG, Henderson BE, Haiman CA, Ziv E. Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas. Human molecular genetics. 2012;21(8):1907-17. doi: 10.1093/hmg/ddr617. PubMed PMID: 22228098; PMCID: 3313799.
Other Breast Cancer:
Shieh Y, Hu D, Ma L, Huntsman S, Gard CC, Leung JWT, Tice JA, Ziv E, Kerlikowske K, Cummings SR. Joint relative risks for estrogen receptor-positive breast cancer from a clinical model, polygenic risk score, and sex hormones. Breast cancer research and treatment. 2017;166(2):603-12. doi: 10.1007/s10549-017-4430-2. PubMed PMID: 28791495; PMCID: PMC5669824.
Ziv E, Tice JA, Sprague B, Vachon CM, Cummings SR, Kerlikowske K. Using Breast Cancer Risk Associated Polymorphisms to Identify Women for Breast Cancer Chemoprevention. PloS one. 2017;12(1):e0168601. doi: 10.1371/journal.pone.0168601. PubMed PMID: 28107349; PMCID: PMC5249071.
Shieh Y, Hu D, Ma L, Huntsman S, Gard CC, Leung JW, Tice JA, Vachon CM, Cummings SR, Kerlikowske K, Ziv E. Breast cancer risk prediction using a clinical risk model and polygenic risk score. Breast cancer research and treatment. 2016;159(3):513-25. doi: 10.1007/s10549-016-3953-2. PubMed PMID: 27565998; PMCID: PMC5033764.
Hoffman JD, Graff RE, Emami NC, et al. Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk. PLoS Genet. 2017;13(3):e1006690.
Caswell JL, Camarda R, Zhou AY, Huntsman S, Hu D, Brenner SE, Zaitlen N, Goga A, Ziv E. Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors. Human molecular genetics. 2015;24(25):7421-31. doi: 10.1093/hmg/ddv432. PubMed PMID: 26472073; PMCID: 4664170
Caswell JL, Kerlikowske K, Shepherd JA, Cummings SR, Hu D, Huntsman S, Ziv E. High mammographic density in women of Ashkenazi Jewish descent. Breast cancer research : BCR. 2013;15(3):R40. doi: 10.1186/bcr3424. PubMed PMID: 23668689.
Genetics of Multiple Myeloma:
Ziv E, Dean E, Hu D, et al. Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients. Nat Commun. 2015;6:7539.
Rand KA, Song C, Dean E, et al. A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci. Cancer Epidemiol Biomarkers Prev. 2016;25(12):1609-1618.